[#item_full_content] DEA has issued new guidance that reaffirms that Timely Applicants and approved DEA registrants may only conduct business with one another as part of the “closed loop” system. The guidance sets a November 29, 2026, deadline to complete sufficient due diligence and establish compliant supply chains. DEA has also moved to deny at least one Minnesota applicant, citing the structure of the state’s cannabis program. 
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DEA Medical Cannabis Shake-Ups: Orders to Show Cause and Due Diligence Timeline for Supply Chain: Vicente LLP
ByPot Shop News
November 5, 2026